Proteases of Dermatophagoides pteronyssinus
نویسندگان
چکیده
منابع مشابه
Proteases of Dermatophagoides pteronyssinus
Since the discovery that Der p 1 is a cysteine protease, the role of proteolytic activity in allergic sensitization has been explored. There are many allergens with proteolytic activity; however, exposure from dust mites is not limited to allergens. In this paper, genomic, transcriptomic and proteomic data on Dermatophagoides pteronyssinus (DP) was mined for information regarding the complete d...
متن کاملDermatophagoides pteronyssinus and bioelectric properties of airway epithelium: role of cysteine proteases.
Several epidemiological studies suggest that exposure to house dust mite allergens plays a role in the pathogenesis of asthma. Since many of these allergens exhibit enzymatic properties, they may damage the airway epithelium. To characterize the effects of low doses of Dermatophagoides pteronyssinus on the airway epithelium, the effect of D. pteronyssinus on the epithelial bioelectric propertie...
متن کاملThe role of Dermatophagoides pteronyssinus in atopic dermatitis.
The role of Dermatophagoides (D.) pteronyssinus in atopic dermatitis (AD) was investigated by use of skin prick test (SPT) and total and specific IgE (RAST) to D. pteronyssinus. The study included 43 patients (17 male and 26 female), mean age 42.3 (range 19-77) years. All study patients met the Hanifin and Rajka criteria. Patients were divided into two groups: "pure" AD (n=27; 12 male and 15 fe...
متن کاملAssociation Between Asthma and Sensitization to Allergens of Dermatophagoides pteronyssinus.
BACKGROUND AND OBJECTIVE Little is known about the role of molecular diagnosis in house dust mite (HDM) allergy. In this study, we investigated the association between the sensitization profile of adolescent and adult HDM-allergic patients and asthma in a region with high rates of exposure to HDM. METHODS We conducted a cross-sectional study of 384 HDM-allergic patients (38.5%, males; median ...
متن کاملCorrelation between skin tests to Dermatophagoides pteronyssinus, Dermatophagoides siboney and Blomia tropicalis in Cuban asthmatics.
BACKGROUND Dermatophagoides pteronyssinus, Dermatophagoides siboney and Blomia tropicalis are the most important allergenic mites in Cuba. The aim of this study was to determine the degree of polysensitization and correlation of the skin prick test (SPT) reaction size to these mites in asthmatic patients. METHODS A total of 232 adult patients with asthmatic symptoms caused by house dust and p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2017
ISSN: 1422-0067
DOI: 10.3390/ijms18061204